2024, Vol 14, No. 3

Editor-in-Chief

Prof. Khosro Adibkia

Original Research

1. In silico design of a triple-negative breast cancer vaccine by targeting cancer testis antigens

Sepideh Parvizpour, Jafar Razmara, Mohammad M. Pourseif, Yadollah Omidi*

Bioimpacts. 2019;9(1): 45-56. doi: 10.15171/bi.2019.06

PMCID: PMC6378095 PMID: 30788259 Scopus ID: 85060470196

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Using immunoinformatic tools, a multi-epitope peptide vaccine (consisting of CD8+cytotoxic T lymphocytes epitopes, helper epitopes and adjuvant) was designed to combat the triple-negative breast cancer. The vaccine showed acceptable immunogenicity and potential to stimulate both cellular and humoral immune responses.

Original Research

2. Designing multi-epitope based peptide vaccine candidates against SARS-CoV-2 using immunoinformatics approach

Ysrafil Ysrafil* , Zulfiayu Sapiun , Indwiani Astuti , Mohammad Anas Anasiru, Nangsih Sulastri Slamet , Hartati Hartati , Fadli Husain, Sukmawati Ahmad Damiti

BioImpacts. 2022;12(4): 359-370. doi: 10.34172/bi.2022.23769

PMCID: PMC9376164 PMID: 35975206 Scopus ID: 85138027836

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The two designed and constructed multiepitope vaccine have good characteristics and may have the potential to activate humoral and cellular immune responses against SARS-CoV-2. Further research is worth considering to confirm the findings of this study.

Original Article

3. Design and computational analysis of an effective multi-epitope vaccine candidate using subunit B of cholera toxin as a build-in adjuvant against urinary tract infections

Maryam Rezaei , Mehri Habibi, Parasoo Ehsani, Mohammad Reza Asadi Karam*, Saeid Bouzari*

Bioimpacts. 2024;14(1): 27513. doi: 10.34172/bi.2023.27513

PMCID: PMC10844585 PMID: 38327629

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As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences.
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